Recombinant Mouse Dync1i1 Protein, Myc/DDK-tagged

• Cat.No.: Dync1i1-2695M
• Product Overview: Purified recombinant protein of mouse full-length dynein cytoplasmic 1 intermediate chain 1 (Dync1i1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 70.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dync1i1 dynein cytoplasmic 1 intermediate chain 1 [ Mus musculus (house mouse) ]
• Official Symbol: Dync1i1
• Synonyms: DYNC1I1; dynein cytoplasmic 1 intermediate chain 1; cytoplasmic dynein 1 intermediate chain 1; dynein, cytoplasmic, intermediate chain 1; cytoplasmic dynein intermediate chain 1 isoform 1.6; Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic dynein intermediate chain 1); DIC; IC74; DHIC-1; Dncic1; DH IC-1
• Gene ID: 13426
• mRNA Refseq: NM_010063
• Protein Refseq: NP_034193
• UniProt ID: O88485