Recombinant Mouse Fkbp5 Protein, Myc/DDK-tagged

• Cat.No.: Fkbp5-3028M
• Product Overview: Purified recombinant protein of mouse full-length FK506 binding protein 5 (Fkbp5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 51.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fkbp5 FK506 binding protein 5 [ Mus musculus (house mouse) ]
• Official Symbol: Fkbp5
• Synonyms: Fkbp5; FK506 binding protein 5; Dit; Dit1; FKBP-5; FKBP51; D17Ertd592; D17Ertd592e; peptidyl-prolyl cis-trans isomerase FKBP5; 51 kDa FK506-binding protein; 51 kDa FKBP; PPIase FKBP5; rotamase; EC 5.2.1.8
• Gene ID: 14229
• mRNA Refseq: NM_010220
• Protein Refseq: NP_034350
• UniProt ID: Q64378