Recombinant Mouse Fkrp Protein, Myc/DDK-tagged

• Cat.No.: Fkrp-3033M
• Product Overview: Purified recombinant protein of mouse full-length fukutin related protein (Fkrp), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the transfer of CDP-ribitol to ribitol 5-phosphate previously attached by FKTN/fukutin of to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the second step in the formation of the ribose 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 55.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fkrp fukutin related protein [ Mus musculus (house mouse) ]
• Official Symbol: Fkrp
• Synonyms: Fkrp; fukutin related protein; LGMD; MDC1C; LGMD1I; AI842067; AI847300; A830029B19Rik; fukutin-related protein; ribitol-5-phosphate transferase
• Gene ID: 243853
• mRNA Refseq: NM_173430
• Protein Refseq: NP_775606
• UniProt ID: Q8CG64