Recombinant Mouse Gm2a Protein, Myc/DDK-tagged
Cat.No. : | Gm2a-3241M |
Product Overview : | Purified recombinant protein of mouse full-length GM2 ganglioside activator protein (Gm2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity. Has cholesterol transfer activity. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 20.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Gm2a GM2 ganglioside activator protein [ Mus musculus (house mouse) ] |
Official Symbol : | Gm2a |
Synonyms : | GM2A; GM2 ganglioside activator protein; ganglioside GM2 activator; shingolipid activator protein 3; cerebroside sulfate activator protein; SAP-3; GM2-AP; AA408702; AW215435 |
Gene ID : | 14667 |
mRNA Refseq : | NM_010299 |
Protein Refseq : | NP_034429 |
UniProt ID : | Q60648 |
Products Types
◆ Recombinant Protein | ||
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GM2A-128H | Recombinant Human GM2A Protein (Met1-Ile193), C-His tagged, Animal-free, Carrier-free | +Inquiry |
GM2A-5001H | Recombinant Human GM2A Protein, GST-tagged | +Inquiry |
GM2A-2972H | Recombinant Human GM2A protein, His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
GM2A-450HCL | Recombinant Human GM2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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