Recombinant Mouse Gpm6a Protein, Myc/DDK-tagged

• Cat.No.: Gpm6a-3289M
• Product Overview: Purified recombinant protein of mouse full-length glycoprotein m6a (cDNA clone MGC:32434 IMAGE:5041793), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 29.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gpm6a glycoprotein m6a [ Mus musculus (house mouse) ]
• Official Symbol: Gpm6a
• Synonyms: Gpm6a; glycoprotein m6a; M6; Gpm; M6A; Gpm6; neuronal membrane glycoprotein M6-a
• Gene ID: 234267
• mRNA Refseq: NM_153581
• Protein Refseq: NP_705809
• UniProt ID: P35802