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Recombinant Mouse HAVCR2 Protein (ECD), Fc-His-tagged(C-ter)

Cat.No. : Havcr2-112M
Product Overview : Recombinant Mouse HAVCR2 Protein (ECD) with Fc-His tag (C-ter) was expressed in HEK293.
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  • Gene Information
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Description : The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Source : HEK293
Species : Mouse
Tag : Fc-His(C-ter)
Form : Powder
Protein Length : Arg20-Arg191
Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
Purity : > 95% (by SDS-PAGE)
Applications : Binding, ELISA, SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 7.4)
Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.
Gene Name : Havcr2 hepatitis A virus cellular receptor 2 [ Mus musculus ]
Official Symbol : Havcr2
Synonyms : HAVCR2; hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; TIMD-3; HAVcr-2; T-cell membrane protein 3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; Tim3; TIM-3; Timd3; MGC124149; MGC124150;
Gene ID : 171285
mRNA Refseq : NM_134250
Protein Refseq : NP_599011

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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