Recombinant Mouse Hmg20a Protein, Myc/DDK-tagged

• Cat.No.: Hmg20a-3411M
• Product Overview: Purified recombinant protein of mouse full-length high mobility group 20A (Hmg20a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hmg20a high mobility group 20A [ Mus musculus (house mouse) ]
• Official Symbol: Hmg20a
• Synonyms: HMG20A; high mobility group 20A; high mobility group protein 20A; inhibitor of BRAF35; HMG box-containing protein 20A; HMG domain-containing protein HMGX1; Ibraf; Hmgxb1; 1200004E06Rik; 5730490E10Rik
• Gene ID: 66867
• mRNA Refseq: NM_025812
• Protein Refseq: NP_080088
• UniProt ID: Q9DC33