Active Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 488 conjugated
Cat.No. : | Il3ra-5661MAF488 |
Product Overview : | Alexa Fluor 488 conjugated recombinant mouse Il3ra protein was expressed in Spodopterafrugiperdawith the Fc part of Human IgG1 Pro100-Lys330 (C-terminus) and MouseIl3ra Ser17-Lys331 (N-terminus). |
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Description : | Il3ra isa pleiotropic cytokine produced primarily by activated T cells or mast cells.Il3ra stimulates the proliferation and differentiation of hemopoietic cellsincluding the pluripotent hematopoietic stem cells as well as various lineage-committedcells. The biological effects of Il3ra on the various cell types are mediatedby the binding of Il3ra to specific cell surface receptor complexes. Thefunctional high-affinity IL-3 receptor is a heterodimer consisting of aligand binding α subunit and the β subunit. The α subunit alone binds Il3rawith low affinity. |
Source : | Insect cells |
Species : | Mouse |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Measuredby its ability to inhibit the IL-3-induced proliferation of NFS-60 mouse myeloidcells. The ED50 for this effect is typically 0.03-0.15 μg/mL in the presenceof 2.5 μg/mL Recombinant Mouse IL-3 Rβ Fc Chimera and 2 ng/mL of RecombinantMouse Il3ra. |
Molecular Mass : | 61.0 kDa (monomer); SDS-PAGE: 70-80kDa, reducing conditions. |
N-terminal Sequence Analysis : | Ser 17 |
Endotoxin : | < 1.0 EU/ μg of the protein by the LAL method. |
Purity : | > 90 % by SDS-PAGE and analyzed by silver stain |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 488 via amines Excitation Wavelength: 488 nm Emission Wavelength: 515-545 nm |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Concentration : | 100 μg/mL |
Storage Buffer : | Lyophilizedfrom a 0.2 μm filtered solution in PBS. |
Reconstitution : | 100 μg/mL in sterile PBS |
Gene Name : | Il3ra interleukin 3 receptor,alpha chain [ Mus musculus ] |
Official Symbol : | Il3ra |
Synonyms : | Il3ra; interleukin 3receptor, alpha chain; CD123; SUT-1; CDw123; interleukin-3 receptor subunit alpha; IL-3RA; IL-3R-alpha; Il-3 alpha subunit; IL-3R subunit alpha; IL-3 receptor alpha chain; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; interleukin-3 receptor class II alpha chain |
Gene ID : | 16188 |
mRNA Refseq : | NM_008369 |
Protein Refseq : | NP_032395 |
UniProt ID : | P26952 |
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IL3RA-202H | Recombinant Human IL3RA Protein (ECD), His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL3RA-742CCL | Recombinant Canine IL3RA cell lysate | +Inquiry |
IL3RA-2433HCL | Recombinant Human IL3RA cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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