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Active Recombinant Mouse Il7 Protein, His-Tagged

Cat.No. : Il7-01M
Product Overview : Recombinant mouse Il7 Protein, His-tagged was expressed in E. coli cell
  • Specification
  • Gene Information
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Description : Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. IL-7 stimulates the differentiation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. It is important for proliferation during certain stages of B-cell maturation, T and NK cell survival, development and homeostasis.
Source : Escherichia coli
Species : Mouse
Tag : His
Form : Lyophilized powder
AA Sequence : MECHIKDKEGKAYESVLMISIDELD KMTGTDSNCPNNEPNFFRKHVCDDT KEAAFLNRAARKLKQFLKMNISEEF NVHLLTVSQGTQTLVNC
TSKEEKNVKEQKKNDACFLKRLLRE IKTCWNKILKGSI with polyhistidine tag at the C-terminus
Endotoxin : <0.1 EU per 1 μg of the protein by the LAL method.
Bio-activity : Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBMC). The ED50 for this effect is <0.2 ng/mL. The specific activity of recombinant mouse IL-7 is > 5 x 10^6 IU/mg.
Purity : >98% as determined by SDS-PAGE. Ni-NTA chromatography
Storage Buffer : The protein was lyophilized from a solution containing 1X PBS, pH 7.4.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Storage : Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C.
Notes : Please use within one month after protein reconstitution.
Gene Name : Il7 interleukin 7 [ Mus musculus (house mouse) ]
Official Symbol : Il7
Synonyms : Il-7; hlb368; A630026I06Rik
Gene ID : 16196
mRNA Refseq : NM_001313888.1
Protein Refseq : NP_001300817.1
UniProt ID : A0A8C6HCD6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What are the application scenarios of IL7? 10/10/2020

IL7 is widely used in the research and development of immunotherapy protocols, can enhance the body's immune function, for the treatment of cancer, infection, autoimmune diseases and other diseases.

What is the mechanism of IL7 in the treatment of bladder cancer? 11/25/2019

IL7 can activate the body's immune system and enhance the immune cells' attack on bladder cancer.

What is the optimal dose of IL7 in the treatment of leukemia? 07/18/2019

The dosage of IL7 in the treatment of leukemia needs to be calculated individually according to the specific situation of the patient.

Does the efficacy of IL7 in the treatment of infectious diseases? 04/10/2019

It can enhance the function of the body's immune system, and has a certain effect on some infectious diseases.

Are there have any efficacy of IL7 in the treatment of specific cancers? 03/31/2019

Recombinant IL7 protein may have some therapeutic effect on specific cancers by activating T cells, but further clinical studies are needed.

How to prepare IL7? 03/27/2019

This is obtained by recombinant DNA technology, inserting foreign genes into the host expression system, and then through purification and other steps.

Customer Reviews (3)

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Reviews
03/27/2022

    Effective in signal transduction pathway.

    04/17/2021

      IL7 has good absorbability and high bioavailability.

      11/27/2020

        Good stability under different environmental conditions

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