Active Recombinant Mouse Il7 Protein, His-Tagged
Cat.No. : | Il7-01M |
Product Overview : | Recombinant mouse Il7 Protein, His-tagged was expressed in E. coli cell |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. IL-7 stimulates the differentiation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. It is important for proliferation during certain stages of B-cell maturation, T and NK cell survival, development and homeostasis. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MECHIKDKEGKAYESVLMISIDELD KMTGTDSNCPNNEPNFFRKHVCDDT KEAAFLNRAARKLKQFLKMNISEEF NVHLLTVSQGTQTLVNC TSKEEKNVKEQKKNDACFLKRLLRE IKTCWNKILKGSI with polyhistidine tag at the C-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Bio-activity : | Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBMC). The ED50 for this effect is <0.2 ng/mL. The specific activity of recombinant mouse IL-7 is > 5 x 10^6 IU/mg. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Gene Name : | Il7 interleukin 7 [ Mus musculus (house mouse) ] |
Official Symbol : | Il7 |
Synonyms : | Il-7; hlb368; A630026I06Rik |
Gene ID : | 16196 |
mRNA Refseq : | NM_001313888.1 |
Protein Refseq : | NP_001300817.1 |
UniProt ID : | A0A8C6HCD6 |
Products Types
◆ Recombinant Protein | ||
IL7-1056H | Recombinant Human IL7 Protein, His-tagged | +Inquiry |
Il7-1683M | Recombinant Mouse Il7 Protein, His-tagged | +Inquiry |
IL7-188M | Active Recombinant Mouse IL7 Protein | +Inquiry |
IL7-2077R | Recombinant Rhesus Macaque IL7 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL7-2172M | Recombinant Mouse IL7 Protein | +Inquiry |
◆ Lysates | ||
IL7-5223HCL | Recombinant Human IL7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIL7 is widely used in the research and development of immunotherapy protocols, can enhance the body's immune function, for the treatment of cancer, infection, autoimmune diseases and other diseases.
IL7 can activate the body's immune system and enhance the immune cells' attack on bladder cancer.
The dosage of IL7 in the treatment of leukemia needs to be calculated individually according to the specific situation of the patient.
It can enhance the function of the body's immune system, and has a certain effect on some infectious diseases.
Recombinant IL7 protein may have some therapeutic effect on specific cancers by activating T cells, but further clinical studies are needed.
This is obtained by recombinant DNA technology, inserting foreign genes into the host expression system, and then through purification and other steps.
Customer Reviews (3)
Write a reviewEffective in signal transduction pathway.
IL7 has good absorbability and high bioavailability.
Good stability under different environmental conditions
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