Recombinant Mouse Itga5 Protein, Myc/DDK-tagged

• Cat.No.: Itga5-3596M
• Product Overview: Purified recombinant protein of mouse full-length integrin alpha 5 (fibronectin receptor alpha) (Itga5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain, which is proteolytically processed to generate light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling. Integrin alpha 5 and integrin alpha V chains are produced by distinct genes. Homozygous knockout mice for this gene exhibit embryonic lethality. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 115.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Itga5 integrin alpha 5 (fibronectin receptor alpha) [ Mus musculus (house mouse) ]
• Official Symbol: Itga5
• Synonyms: ITGA5; integrin alpha 5 (fibronectin receptor alpha); integrin alpha-5; integrin alpha-F; CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor alpha polypeptide; Fnra; VLA5; Cd49e
• Gene ID: 16402
• mRNA Refseq: NM_010577
• Protein Refseq: NP_034707
• UniProt ID: P11688