Recombinant Mouse Josd1 Protein, Myc/DDK-tagged

• Cat.No.: Josd1-3634M
• Product Overview: Purified recombinant protein of mouse full-length Josephin domain containing 1 (Josd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 23.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Josd1 Josephin domain containing 1 [ Mus musculus (house mouse) ]
• Official Symbol: Josd1
• Synonyms: JOSD1; Josephin domain containing 1; Josephin-1; josephin domain-containing protein 1; mKIAA0063; MGC6306; 1300006C06Rik; MGC101975
• Gene ID: 74158
• mRNA Refseq: NM_028792
• Protein Refseq: NP_083068
• UniProt ID: Q9DBJ6