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Recombinant Mouse Lgals3 protein, His-tagged

Cat.No.: Lgals3-190M
Product Overview: Recombinant mouse LGALS3 protein, used to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.
Source: E.coli
Species: Mouse
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,50% glycerol,1mM DTT, 2mM EDTA
Bio-activity: The ED50 for this effect is equal or higher than 25 ug/ml. Measured by its ability to agglutinate human red blood cells.
Molecular Mass: 29.8 kDa (287aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAPGAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRFNENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI
Purity: > 95% by SDS - PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: Lgals3 lectin, galactose binding, soluble 3 [ Mus musculus ]
Official Symbol: Lgals3
Synonyms: LGALS3; lectin, galactose binding, soluble 3; galectin-3; gal-3; CBP 35; lectin L-29; 35 kDa lectin; mac-2 antigen; igE-binding protein; laminin-binding protein; galactose-specific lectin 3; L-34 galactoside-binding lectin; carbohydrate-binding protein 35; GBP; L-34; gal3; Mac-2;
Gene ID: 16854
mRNA Refseq: NM_001145953
Protein Refseq: NP_001139425
MIM:
UniProt ID:
Function: protein binding; sugar binding;

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