Recombinant Mouse Mettl1 Protein, Myc/DDK-tagged
Cat.No. : | Mettl1-4040M |
Product Overview : | Purified recombinant protein of mouse full-length methyltransferase like 1 (Mettl1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Methyltransferase that mediates the formation of N7-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs). Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA. Also acts as a methyltransferase for a subset of internal N7-methylguanine in mRNAs. Internal N7-methylguanine methylation of mRNAs regulates translation. Also methylates a specific subset of miRNAs, such as let-7. N7-methylguanine methylation of let-7 miRNA promotes let-7 miRNA processing by disrupting an inhibitory secondary structure within the primary miRNA transcript (pri-miRNA). Acts as a regulator of embryonic stem cell self-renewal and differentiation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 30.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Mettl1 methyltransferase like 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Mettl1 |
Synonyms : | METTL1; methyltransferase like 1; tRNA (guanine-N(7)-)-methyltransferase; methyltransferase-like 1; tRNA(m7G46)-methyltransferase; methyltransferase-like protein 1; tRNA (guanine(46)-N(7))-methyltransferase; 2810012D02Rik |
Gene ID : | 17299 |
mRNA Refseq : | NM_010792 |
Protein Refseq : | NP_034922 |
UniProt ID : | Q9Z120 |
Products Types
◆ Recombinant Protein | ||
METTL1-4411H | Recombinant Human METTL1 Protein, GST-tagged | +Inquiry |
METTL1-5487M | Recombinant Mouse METTL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
METTL1-946H | Recombinant Human METTL1 Protein, MYC/DDK-tagged | +Inquiry |
METTL1-866H | Recombinant Human METTL1 protein, His-tagged | +Inquiry |
METTL1-9745M | Recombinant Mouse METTL1 Protein | +Inquiry |
◆ Lysates | ||
METTL1-1080HCL | Recombinant Human METTL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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