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Recombinant Mouse Mif Protein, Myc/DDK-tagged

Cat.No. : Mif-4073M
Product Overview : Purified recombinant protein of mouse full-length macrophage migration inhibitory factor (glycosylation-inhibiting factor) (Mif), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 12.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) [ Mus musculus (house mouse) ]
Official Symbol : Mif
Synonyms : MIF; macrophage migration inhibitory factor; DER6; L-dopachrome isomerase; L-dopachrome tautomerase; phenylpyruvate tautomerase; glycosylation-inhibiting factor; delayed early response protein 6; GIF; Glif; MGC107654
Gene ID : 17319
mRNA Refseq : NM_010798
Protein Refseq : NP_034928
UniProt ID : P34884

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does MIF contribute to autoimmune diseases? 07/30/2022

MIF can promote inflammation and immune responses, contributing to autoimmune diseases like rheumatoid arthritis and systemic lupus erythematosus.

How does MIF influence neuroinflammation? 10/01/2021

MIF is involved in the regulation of neuroinflammation and has implications in neurodegenerative diseases like Alzheimer's.

What are some conditions where MIF is implicated in clinical applications? 12/22/2019

MIF is implicated in conditions like autoimmune diseases, sepsis, and cancer.

Can MIF be a potential therapeutic target in autoimmune diseases? 08/20/2019

Yes, targeting MIF with drugs or antibodies is being explored as a potential treatment for autoimmune diseases.

What are some other clinical applications of MIF? 02/26/2019

MIF is also studied in the context of cardiovascular diseases, neuroinflammation, and wound healing.

Customer Reviews (3)

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Reviews
12/05/2022

    The cost-effectiveness of the MIF protein, competitive pricing, and the availability of bulk purchase options provided by the manufacturer also align with my budget considerations, allowing me to optimize my resources.

    10/13/2016

      the manufacturer's commitment to delivering the MIF protein in a timely manner is greatly appreciated.

      06/06/2016

        the excellent technical support provided by the manufacturer is of immense value to me.

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