Recombinant Mouse Naxe Protein, Myc/DDK-tagged

• Cat.No.: Naxe-4299M
• Product Overview: Purified recombinant protein of mouse full-length NAD(P)HX epimerase (Naxe), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 31 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Naxe NAD(P)HX epimerase [ Mus musculus (house mouse) ]
• Official Symbol: Naxe
• Synonyms: Naxe; NAD(P)HX epimerase; AI; AP; AIBP; AI-BP; ESTM3; ESTM37; Apoa1bp; Apoa1ip; AA087124; NAD(P)H-hydrate epimerase; apoA-I binding protein; apolipoprotein A-I binding protein; apolipoprotein A-I interacting protein; EC 5.1.99.6
• Gene ID: 246703
• mRNA Refseq: NM_144897
• Protein Refseq: NP_659146
• UniProt ID: Q8K4Z3