Recombinant Mouse Nck2 Protein, Myc/DDK-tagged

• Cat.No.: Nck2-4311M
• Product Overview: Purified recombinant protein of mouse full-length non-catalytic region of tyrosine kinase adaptor protein 2 (Nck2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 42.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Nck2
• Synonyms: NCK2; non-catalytic region of tyrosine kinase adaptor protein 2; cytoplasmic protein NCK2; NCK adaptor protein 2; SH2/SH3 adaptor protein NCK-beta; growth factor receptor-bound protein 4; Grb4; Nck-2; NCKbeta; 4833426I10Rik
• Gene ID: 17974
• mRNA Refseq: NM_010879
• Protein Refseq: NP_035009
• UniProt ID: O55033