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Recombinant Mouse Ntan1 Protein, Myc/DDK-tagged

Cat.No. : Ntan1-4518M
Product Overview : Purified recombinant protein of mouse full-length N-terminal Asn amidase (Ntan1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene functions in a step-wise protein degradation process through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asparagine residues on proteins to produce N-terminal L-Aspartate. L-Aspartate substrates are subsequently conjugated to L-Arginine, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Mice with a knock-out of this gene are viable, fertile, and outwardly normal, but show impairments in spontaneous activity and spatial memory, relative to their wild-type counterparts. Alternative splicing results in multiple transcript variants.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 34.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ntan1 N-terminal Asn amidase [ Mus musculus (house mouse) ]
Official Symbol : Ntan1
Synonyms : NTAN1; N-terminal Asn amidase; protein N-terminal asparagine amidohydrolase; PNAA; PNAD; protein NTN-amidase; protein N-terminal Asn amidase; N-terminal asparagine amidohydrolase; asparagine-specific N-terminal amidase; protein NH2-terminal asparagine deamidase; protein NH2-terminal asparagine amidohydrolase
Gene ID : 18203
mRNA Refseq : NM_010946
Protein Refseq : NP_035076
UniProt ID : Q64311

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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