Recombinant Mouse Ntrk3 Protein, Myc/DDK-tagged

• Cat.No.: Ntrk3-4524M
• Product Overview: Purified recombinant protein of mouse full-length neurotrophic tyrosine kinase, receptor, type 3 (Ntrk3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 93.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 [ Mus musculus (house mouse) ]
• Official Symbol: Ntrk3
• Synonyms: NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; trk-C; GP145-TrkC; neurotrophin-3; trkC tyrosine kinase; TrkC; AW125844; Ntrk3_tv3
• Gene ID: 18213
• mRNA Refseq: NM_008746
• Protein Refseq: NP_032772
• UniProt ID: Q6VNS1