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Recombinant Mouse Ptpn5 Protein, Myc/DDK-tagged

Cat.No. : Ptpn5-5241M
Product Overview : Purified recombinant protein of mouse full-length protein tyrosine phosphatase, non-receptor type 5 (Ptpn5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 60.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ptpn5 protein tyrosine phosphatase, non-receptor type 5 [ Mus musculus (house mouse) ]
Official Symbol : Ptpn5
Synonyms : PTPN5; protein tyrosine phosphatase, non-receptor type 5; tyrosine-protein phosphatase non-receptor type 5; neural-specific protein-tyrosine phosphatase; striatum-enriched protein-tyrosine phosphatase; Step
Gene ID : 19259
mRNA Refseq : NM_001163565
Protein Refseq : NP_001157037
UniProt ID : P54830

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How is PTPN5 protein related to tumorigenesis? 09/11/2021

PTPN5 protein is aberrantly expressed in some types of tumors and may be involved in tumor formation and development by regulating signaling pathways.

What is the role of PTPN5 protein in brain development and maturation? 09/07/2021

This protein is involved in key events such as neuronal differentiation, migration, and synapse formation during brain development and maturation.

How is the enzymatic activity of PTPN5 protein regulated? 04/13/2021

The enzymatic activity of PTPN5 protein may be regulated by mechanisms such as phosphorylation modification and protein-protein interactions.

How about the therapeutic potential of PTPN5 protein in neurodegenerative diseases? 12/12/2020

The protein is being studied as a potential therapeutic target for neurodegenerative diseases, but there is no specific clinical application.

Is PTPN5 protein associated with depression or psychiatric disorders? 10/16/2020

PTPN5 protein may be associated with neuropsychiatric diseases such as depression and psychiatric disorders, but the specific mechanism needs to be further studied.

Is there a link between PTPN5 protein and cognitive function? 08/01/2020

Studies have shown that PTPN5 protein may be associated with cognitive functions (such as learning Xi memory), but the specific mechanism and role need to be further studied.

Customer Reviews (3)

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Reviews
06/03/2023

    The structural integrity of PTPN5 was verified, and the folding state and secondary structure were consistent with native proteins.

    06/24/2022

      PTPN5 has good DNA-binding ability and has performed well in related experiments.

      02/22/2022

        PTPN5 has good stability in solution and is not easy to aggregate or inactivate.

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