Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Ptprs Protein, Myc/DDK-tagged

Cat.No. : Ptprs-5252M
Product Overview : Purified recombinant protein of mouse full-length protein tyrosine phosphatase, receptor type, S (cDNA clone MGC:63375 IMAGE:6834684), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection). Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb. Functions as tyrosine phosphatase. Mediates dephosphorylation of NTRK1, NTRK2 and NTRK3. Plays a role in down-regulation of signaling cascades that lead to the activation of Akt and MAP kinases. Down-regulates TLR9-mediated activation of NF-kappa-B, as well as production of TNF, interferon alpha and interferon beta.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 204.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ptprs protein tyrosine phosphatase, receptor type, S [ Mus musculus (house mouse) ]
Official Symbol : Ptprs
Synonyms : Ptprs; protein tyrosine phosphatase, receptor type, S; PTP; RPT; PTP-; Ptpt9; PTP-NU3; PTPNU-3; R-PTP-S; AL022616; PTPsigma; RPTPsigma; receptor-type tyrosine-protein phosphatase S; R-PTP-sigma; Receptor-type tyrosine-protein phosphatase sigma; tissue-specific protein tyrosine phosphatase; EC 3.1.3.48
Gene ID : 19280
mRNA Refseq : NM_011218
Protein Refseq : NP_035348
UniProt ID : B0V2N1

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Ptprs Products

Required fields are marked with *

My Review for All Ptprs Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends