Recombinant Mouse Rab11b Protein, Myc/DDK-tagged
Cat.No. : | Rab11b-5284M |
Product Overview : | Purified recombinant protein of mouse full-length RAB11B, member RAS oncogene family (Rab11b), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11B plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 24.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Rab11b RAB11B, member RAS oncogene family [ Mus musculus (house mouse) ] |
Official Symbol : | Rab11b |
Synonyms : | RAB11B; RAB11B, member RAS oncogene family; ras-related protein Rab-11B; A730055L17Rik |
Gene ID : | 19326 |
mRNA Refseq : | NM_008997 |
Protein Refseq : | NP_033023 |
UniProt ID : | P46638 |
Products Types
◆ Recombinant Protein | ||
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RAB11B-7337M | Recombinant Mouse RAB11B Protein, His (Fc)-Avi-tagged | +Inquiry |
RAB11B-1825H | Recombinant Human RAB11B Protein, His (Fc)-Avi-tagged | +Inquiry |
RAB11B-1924C | Recombinant Chicken RAB11B | +Inquiry |
◆ Lysates | ||
RAB11B-2630HCL | Recombinant Human RAB11B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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