Recombinant Mouse Sema7a Protein, Myc/DDK-tagged

• Cat.No.: Sema7a-5763M
• Product Overview: Purified recombinant protein of mouse full-length sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (Sema7a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 75.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sema7a sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A [ Mus musculus (house mouse) ]
• Official Symbol: Sema7a
• Synonyms: SEMA7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; semaphorin-7A; sema L; sema K1; H-Sema K1; semaphorin-L; Semaphorin K1; semaphorin-K1; Semal; CDw108; H-Sema-L; M-Sema-L; 2900057C09Rik
• Gene ID: 20361
• mRNA Refseq: NM_011352
• Protein Refseq: NP_035482
• UniProt ID: Q9QUR8