Recombinant Mouse Sox2 Protein, Myc/DDK-tagged

• Cat.No.: Sox2-6054M
• Product Overview: Purified recombinant protein of mouse full-length SRY (sex determining region Y)-box 2 (Sox2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in a similar gene in human have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (Sox2ot).
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 34.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sox2 SRY (sex determining region Y)-box 2 [ Mus musculus (house mouse) ]
• Official Symbol: Sox2
• Synonyms: Sox2; SRY (sex determining region Y)-box 2; lc; ys; Sox; lcc; ysb; Sox-2; transcription factor SOX-2; SRY-box containing gene 2
• Gene ID: 20674
• mRNA Refseq: NM_011443
• Protein Refseq: NP_035573
• UniProt ID: P48432