Recombinant Mouse Sra1 Protein, Myc/DDK-tagged

• Cat.No.: Sra1-6121M
• Product Overview: Purified recombinant protein of mouse full-length steroid receptor RNA activator 1 (Sra1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 24.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sra1 steroid receptor RNA activator 1 [ Mus musculus (house mouse) ]
• Official Symbol: Sra1
• Synonyms: SRA1; steroid receptor RNA activator 1; steroid receptor RNA activator protein; Sra; Srap; Straa1; Strra1; AA959952
• Gene ID: 24068
• mRNA Refseq: NM_025291
• Protein Refseq: NP_079567
• UniProt ID: Q80VJ2