Recombinant Mouse Tgfb1i1 Protein, Myc/DDK-tagged

• Cat.No.: Tgfb1i1-6388M
• Product Overview: Purified recombinant protein of mouse full-length transforming growth factor beta 1 induced transcript 1 (Tgfb1i1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 48.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tgfb1i1 transforming growth factor beta 1 induced transcript 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tgfb1i1
• Synonyms: TGFB1I1; transforming growth factor beta 1 induced transcript 1; transforming growth factor beta-1-induced transcript 1 protein; TGF beta-stimulated clone 5; hydrogen peroxide-inducible clone 5 protein; androgen receptor-associated protein of 55 kDa; Hic5; ARA55; TSC-5; hic-5
• Gene ID: 21804
• mRNA Refseq: NM_009365
• UniProt ID: Q62219