Recombinant Mouse Tgfb3 Protein, Myc/DDK-tagged

• Cat.No.: Tgfb3-6390M
• Product Overview: Purified recombinant protein of mouse full-length transforming growth factor, beta 3 (Tgfb3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Homozygous knockout mice for this gene exhibit cleft palate, delayed pulmonary development and neonatal death. [provided by RefSeq, Aug 2016]
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 47.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tgfb3 transforming growth factor, beta 3 [ Mus musculus (house mouse) ]
• Official Symbol: Tgfb3
• Synonyms: TGFB3; transforming growth factor, beta 3; transforming growth factor beta-3; TGF-beta-3; Tgfb-3; MGC118722
• Gene ID: 21809
• mRNA Refseq: NM_009368
• Protein Refseq: NP_033394
• UniProt ID: Q3TRQ9