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Recombinant Mouse Trim21 Protein, Myc/DDK-tagged

Cat.No. : Trim21-6646M
Product Overview : Purified recombinant protein of mouse full-length tripartite motif-containing 21 (Trim21), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Ubiquitous expression in thymus adult (RPKM 5.4), bladder adult (RPKM 4.4) and 27 other tissues
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 54.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Trim21 tripartite motif-containing 21 [ Mus musculus (house mouse) ]
Official Symbol : Trim21
Synonyms : TRIM21; tripartite motif-containing 21; E3 ubiquitin-protein ligase TRIM21; SS-A; ro(SS-A); 52 kDa Ro protein; 52kD Ro/SSA autoantigen; Sjogren syndrome antigen A1; tripartite motif protein 21; sjoegren syndrome type A antigen; tripartite motif-containing protein 21; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; Ro52; Ssa1
Gene ID : 20821
mRNA Refseq : NM_001082552
Protein Refseq : NP_001076021
UniProt ID : Q3U7K7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any specific viral infections that TRIM21 is particularly effective against? 10/31/2022

TRIM21 has demonstrated efficacy against a broad range of viruses, including but not limited to influenza, herpes simplex virus, and adenovirus.

How does TRIM21 function in the immune system? 11/14/2020

TRIM21 acts as an intracellular antibody receptor, binding to antibodies that have attached to viruses inside the cell. This binding triggers a process that leads to the destruction of the virus.

What are the potential clinical applications of TRIM21? 02/28/2019

TRIM21 has promising applications in various clinical settings, particularly in the development of therapies for viral infections and autoimmune diseases.

How does TRIM21 contribute to the treatment of autoimmune diseases? 05/15/2017

TRIM21's role in regulating immune responses makes it a potential target for therapies aimed at modulating the immune system in autoimmune diseases.

Can TRIM21 be used in antiviral therapies? 06/05/2016

Yes, TRIM21's ability to target and degrade antibody-bound viruses makes it a potential candidate for antiviral therapies.

Customer Reviews (3)

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Reviews
08/13/2022

    They can provide fast and efficient delivery services, minimizing any potential delays and allowing researchers to proceed with their studies in a timely manner.

    12/30/2020

      The manufacturer can provide researchers with a high-quality, purified form of TRIM21 protein, ensuring its integrity and functionality for experimental use.

      10/11/2017

        A manufacturer with a responsive and dedicated customer support team can address any concerns or queries that researchers may have.

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