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Recombinant Mouse Trim72 protein, His/S-tagged

Cat.No. : Trim72-157M
Product Overview : Recombinant Mouse Trim72 fused with His/S tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The tripartite motif (TRIM) family of proteins are characerized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM72 (tripartite motif containing 72), also known as MG53, is a 477 amino acid cytoplasmic vesicle membrane protein that belongs to the TRIM/RBCC family. Existing as a homooligomer, TRIM72 contains one B box-type zinc finger, one B30.2/SPRY domain and a RING-type zinc finger. TRIM72 is considered a muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. TRIM72 is required for transport of dysferlin to sites of cell injury during repair patch formation. TRIM72 also regulates membrane budding and exocytosis and may be involved in the regulation of the mobility of KV2.1-containing endocytic vesicles. TRIM72 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 16p11.2.
Source : E. coli
Species : Mouse
Tag : His/S
Form : Lyophilized from sterile PBS, pH 7.4
Purity : > 95 % as determined by SDS-PAGE
Storage : Store at -70 centigrade. Avoid repeated freeze/thaw cycles.
Gene Name : Trim72 tripartite motif-containing 72 [ Mus musculus ]
Official Symbol : Trim72
Synonyms : TRIM72; tripartite motif-containing 72; tripartite motif-containing protein 72; mitsugumin 53; mitsugumin-53; MG53; BC067209;
Gene ID : 434246
mRNA Refseq : NM_001079932
Protein Refseq : NP_001073401
UniProt ID : Q1XH17
Chromosome Location : 7; 7 F3
Function : metal ion binding; phosphatidylserine binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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