Recombinant Mouse Tyr Protein, Myc/DDK-tagged
Cat.No. : | Tyr-6757M |
Product Overview : | Purified recombinant protein of mouse full-length tyrosinase (Tyr), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 61.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Tyr tyrosinase [ Mus musculus (house mouse) ] |
Official Symbol : | Tyr |
Synonyms : | TYR; tyrosinase; albino locus protein; monophenol monooxygenase; c; skc35; albino |
Gene ID : | 22173 |
mRNA Refseq : | NM_011661 |
Protein Refseq : | NP_035791 |
UniProt ID : | P11344 |
Products Types
◆ Recombinant Protein | ||
TYR-1551H | Recombinant Human TYR Protein (19-377 aa), His-tagged | +Inquiry |
TYR-9798M | Recombinant Mouse TYR Protein, His (Fc)-Avi-tagged | +Inquiry |
Tyr-518R | Recombinant Rat Tyr Protein, His-tagged | +Inquiry |
TYR-2965H | Recombinant Human TYR Protein, MYC/DDK-tagged | +Inquiry |
TYR-2286H | Recombinant Human TYR Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TYR-1869HCL | Recombinant Human TYR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0836 | Tyrosine Colorimetric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThere are no drugs that directly increase TYR protein levels, but there are drugs that can treat diseases that cause low TYR protein levels.
This protein may play a role in skin aging because it is involved in the production and metabolism of melanin. However, skin aging is also related to other factors, such as genetics, environment, etc.
Some whitening products claim to inhibit the TYR protein, thereby reducing the production of melanin. However, the efficacy and safety of these products have yet to be proven.
It is difficult to directly increase the level of TYR protein through diet because TYR protein is mainly genetically determined. However, the presence of copper in the diet can promote the function of the TYR protein.
TYR is not directly related to tanning. Tanning is a process by which skin cells produce melanin due to ultraviolet rays.
TYR protein may be involved in the occurrence and progression of skin cancer because it is involved in the production and metabolism of melanin.
Customer Reviews (3)
Write a reviewRepeatability is good, the results of multiple experiments are highly consistent, and the repeatability is particularly good.
High solubility, can be dissolved in various types of reagents, easy to operate.
Not easy to inactivate, tried a variety of experimental conditions, still active.
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