Recombinant Mouse Ulk1 Protein, Myc/DDK-tagged
Cat.No. : | Ulk1-6830M |
Product Overview : | Purified recombinant protein of mouse full-length unc-51 like kinase 1 (Ulk1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy. Phosphorylates FLCN, promoting autophagy. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 112.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Ulk1 unc-51 like kinase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Ulk1 |
Synonyms : | ULK1; Unc-51 like kinase 1 (C. elegans); serine/threonine-protein kinase ULK1; unc-51-like kinase 1; serine/threonine-protein kinase Unc51.1; Unc51.1; AU041434; mKIAA0722 |
Gene ID : | 22241 |
mRNA Refseq : | NM_009469 |
Protein Refseq : | NP_033495 |
UniProt ID : | O70405 |
Products Types
◆ Recombinant Protein | ||
ULK1-10H | Active Recombinant Human ULK1 protein, GST&Strep II-Tagged | +Inquiry |
ULK1-557H | Recombinant Human ULK1 Protein, MYC/DDK-tagged | +Inquiry |
ULK1-2313H | Recombinant Human ULK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ULK1-9903M | Recombinant Mouse ULK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ULK1-31666TH | Recombinant Human ULK1, FLAG-tagged | +Inquiry |
◆ Lysates | ||
ULK1-505HCL | Recombinant Human ULK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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