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Recombinant Murine Wnt3a Protein, His/S-tagged

Cat.No. : Wnt3a-09M
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  • Gene Information
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Description : The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008]
Source : E. coli
Species : Mouse
Tag : His, S
Form : Lyophilized from sterile PBS, pH 7.4
Purity : >95% by SDS-PAGE
Storage : Store at -70 centigrade or below. Avoid freeze/thaw.
Gene Name : Wnt3a wingless-related MMTV integration site 3A [ Mus musculus ]
Official Symbol : Wnt3a
Synonyms : WNT3A; wingless-related MMTV integration site 3A; protein Wnt-3a; vestigial tail; vt; Wnt-3a;
Gene ID : 22416
mRNA Refseq : NM_009522
Protein Refseq : NP_033548
Pathway : Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Function : frizzled binding; frizzled-2 binding; protein binding; protein domain specific binding; receptor agonist activity; receptor binding; transcription coactivator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does CDH16 protein interact with WNT3A protein? 12/14/2019

No interaction between CDH16 protein and WNT3A protein has been found.

Which role of WNT3A protein in embryonic development? 09/15/2019

The WNT3A protein plays an important role in embryonic development. It is involved in the formation of multiple embryonic organs, directed cell migration, and the establishment of tissue polarity.

Have regulators of WNT3A protein been identified? 08/24/2019

Yes, multiple factors have been found in the WNT signaling pathway that regulate the expression and function of WNT3A protein, including Axin, APC, etc.

Where is the WNT3A protein in the Wnt signaling pathway? 05/18/2019

The WNT3A protein is in the starting position in the Wnt signaling pathway, and it is able to bind to the Wnt receptor and initiate the signaling cascade.

What is the relationship between WNT3A protein and cancer stem cells? 05/04/2019

WNT3A protein is closely related to cancer stem cells. It may be involved in the self-renewal and differentiation regulation of cancer stem cells, which is of great significance for tumor development and treatment.

How about the current clinical research progress on WNT3A protein? 03/28/2019

Clinical research on WNT3A protein is still ongoing. Studies have shown the important role of WNT3A protein in tumors, neurological diseases, bone metabolism diseases, etc., and future research will further explore its application potential in disease diagnosis, treatment and prognosis assessment.

Customer Reviews (3)

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Reviews
07/15/2022

    This protein is highly expressed and can efficiently synthesize a large number of target proteins in host cells.

    06/03/2022

      This protein has therapeutic effects on specific disease models and is a promising candidate for new drugs.

      11/20/2019

        The laboratory personnel feedback that the protein is easy to operate, can meet the experimental needs, and has a good cost performance.

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