Active Recombinant Rat Cd70 protein, His-tagged
Cat.No. : | Cd70-8731R |
Product Overview : | Recombinant Rat Cd70 protein(NP_001100348)(Gln46-Pro195), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Rat |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1.Measured by its binding ability in a functional ELISA.2.Immobilized rat His-CD70 at 10μg/mL (100μL/well) can bind mouse CD27-Fch, the EC50 of mouse CD27-Fch is 10-50ng/mL. |
Molecular Mass : | The recombinant rat CD70 comprises 170 amino acids and has a predicted molecular mass of 18.9 kDa. The apparent molecular mass of the protein is approximately 28 kDa in SDS-PAGE under reducing conditions. |
Protein Length : | Gln46-Pro195 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Cd70 Cd70 molecule [ Rattus norvegicus ] |
Official Symbol : | Cd70 |
Synonyms : | CD70; Cd70 molecule; CD70 antigen; |
Gene ID : | 301132 |
mRNA Refseq : | NM_001106878 |
Protein Refseq : | NP_001100348 |
Products Types
◆ Recombinant Protein | ||
CD70-437H | Recombinant Human CD70 Protein (Gln39-Pro193), RIgG Fc-tagged | +Inquiry |
Cd70-972M | Active Recombinant Mouse Cd70 protein(Gln47-Pro159), mFc-tagged | +Inquiry |
CD70-0848H | Recombinant Human CD70 Protein | +Inquiry |
CD70-324H | Active Recombinant Human CD70 Protein (Gln39-Pro193), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CD70-623H | Recombinant Human CD70 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CD70-1303RCL | Recombinant Rat CD70 cell lysate | +Inquiry |
CD70-2710HCL | Recombinant Human CD70 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionAntibodies, antibody-drug conjugates, and chimeric antigen receptor (CAR) T-cell therapies are being developed to target CD70 in cancer.
CD70-targeted therapies can enhance the body's immune response against cancer cells and potentially lead to more effective treatments.
CD70 expression is often observed in Hodgkin's lymphoma and certain types of T-cell lymphomas.
Challenges include potential toxicities and finding the right balance to target CD70 effectively without harming normal immune functions.
Yes, there are ongoing clinical trials exploring CD70-targeted therapies for various cancer types.
Customer Reviews (3)
Write a reviewTheir collaboration, expertise, and customized solutions contribute to the successful execution of experiments, reliable data generation, and the advancement of scientific knowledge in the field.
the manufacturer's support is crucial for researchers using CD70 protein in trials.
These resources can enhance the efficiency and accuracy of experimental workflows and contribute to successful outcomes.
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