Active Recombinant Rat Chemokine (C-C motif) Ligand 2
Cat.No. : | Ccl2-469R |
Product Overview : | Recombinant Rat Ccl2protein was expressed in Murine myeloma cell line. Gln24-Asn148. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Ccl2-469R |
Description : | Rat Ccl2 is a memberof the β (CC) subfamily of chemokines that is a chemoattractant for monocytesand basophils but not eosinophils or neutrophils. Rat Ccl2 is secreted as a 14kDa glycoprotein monomer but noncovalent dimers probably occur. The first fiveamino acids of the mature protein are essential for activity; deletion of theN-terminal glutamine, which is pyrrolidone carboxylic acidmodified, dramaticallydecreases activity on basophils and, surprisingly, stimulates eosinophil chemotaxis. |
Source : | Mammalian cells |
Form : | Lyophilized from a 0.2μm filtered solution in PBS with Trehalose and with BSA as a carrier protein. |
N-terminalSequence : | No results obtained:Gln24 predicted |
Molecular Weight : | 14 kDa |
Activity : | Measuredby its ability to chemoattract human CCR2A transfected BaF3 mouse proB cells.The ED50 for this effect is typically 30-150 ng/mL. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 10 μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use a manualdefrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months,-20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Ccl2 chemokine(C-C motif) ligand 2 [ Rattus norvegicus ] |
Official Symbol : | Ccl2 |
Synonyms : | Ccl2; chemokine(C-C motif) ligand 2; MCP-1; Scya2; Sigje; C-C motif chemokine 2; small induciblegene JE; small inducible cytokine A2; small-inducible cytokine A2; monocyte chemotacticprotein 1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1;immediate-early serum-responsive JE protein; immediate-early serum-responsiveprotein JE; Je; Mcp1 |
Gene ID : | 24770 |
mRNA Refseq : | NM_031530 |
Protein Refseq : | NP_113718 |
UniProt ID : | P14844 |
Chromosome Location : | 10q26 |
Pathway : | Chemokine signaling pat |
Function : | CCR2 chemokine receptorbinding; G-protein coupled receptor binding; chemokine activity; heparin binding |
Products Types
◆ Recombinant Protein | ||
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CCL2-14H | Active Recombinant Human CCL2 Protein | +Inquiry |
CCL2-16R | Recombinant Rat CCL2 Protein | +Inquiry |
Ccl2-173C | Active Recombinant Mouse Ccl2 Protein (73 aa) | +Inquiry |
Ccl2-1101R | Recombinant Rat Ccl2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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