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Recombinant Rat Col18a1Protein, His/GST-tagged

Cat.No. : Col18a1-328R
Product Overview : Recombinant Rat Col18a1(Ser1072~Gly1271) fused with His/GST tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Source : E. coli
Species : Rat
Tag : His/GST
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 54.5kDa
Protein length : Ser1072~Gly1271
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : Col18a1 collagen, type XVIII, alpha 1 [ Rattus norvegicus ]
Official Symbol : Col18a1
Synonyms : COL18A1; collagen, type XVIII, alpha 1; procollagen, type XVIII, alpha 1;
Gene ID : 85251
mRNA Refseq : NM_053489
Protein Refseq : NP_445941

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you discuss the role of COL18A1 in neurobiology, particularly its involvement in the central nervous system and potential implications for neurodegenerative disorders? 04/16/2021

COL18A1 has roles in the central nervous system. Understanding its functions provides insights into potential implications for neurodegenerative disorders and neural tissue development.

In angiogenesis, how does COL18A1 influence blood vessel formation, and what molecular mechanisms are involved in its regulation of endothelial cell behavior? 06/02/2020

COL18A1 plays a role in angiogenesis by regulating endothelial cell behavior. It interacts with integrins and growth factors, influencing signaling pathways essential for blood vessel formation.

What evidence supports the involvement of COL18A1 mutations in human diseases, and how do these mutations impact COL18A1 function and tissue homeostasis? 01/19/2019

Mutations in COL18A1 are associated with various diseases. Understanding the impact of these mutations on collagen XVIII function provides insights into their roles in tissue homeostasis and disease pathology.

How does COL18A1 contribute to the regulation of cellular senescence, and are there implications for age-related diseases and tissue degeneration? 12/30/2018

COL18A1 has been implicated in the regulation of cellular senescence. Understanding its role in age-related diseases may provide insights into tissue degeneration and potential therapeutic targets.

In cancer progression, how does COL18A1 influence tumor behavior, metastasis, and interactions with the tumor microenvironment? 08/11/2018

COL18A1 is implicated in cancer progression, affecting tumor behavior and metastasis. Its interactions within the tumor microenvironment contribute to the regulation of invasive phenotypes.

Customer Reviews (3)

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Reviews
06/01/2022

    The delivery was well-coordinated and timely.

    09/12/2019

      Superior quality resonates in this lab product, supported by customer service that is genuinely helpful.

      12/23/2018

        The lab product showcases commendable quality.

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