Active Recombinant Rat Cyp2d4 Protein
| Cat.No. : | Cyp2d4-139R |
| Product Overview : | Recombinant rat CYP2D18 protein and CYP-reductase without tag were coexpressed in E. coli. Amount: 1 nmol cytochrome P450. |
- Specification
- Gene Information
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| Description : | Has N-demethylation activity toward the antidepressant imipramine |
| Source : | E. coli |
| Species : | Rat |
| Bio-activity : | Cytochrome c Reductase Activity: 1531 nmol/min/mg protein P450 Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 50 mM potassium phosphate buffer (pH 7.4) containing 5 mM magnesium chloride and an NADPH generating system [5 mM glucose 6-phosphate, 1 mM NADP+, 1 U/ml glucose 6-phosphate dehydrogenase]) Activity: Dextromethorphan O-demethylase Linear with time up to: 6 min(Determined at 15 µM substrate, using a P450 concentration of 20 pmol/ml) Linear with P450 up to: 40 pmol/ml(Determined at 15 µM substrate, using an incubation time of 5 min) Vmax: 5.1 pmol/min/pmol CYP Km: 39 µM |
| Usage : | For laboratory (research) purposes only |
| Storage : | Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice. |
| Concentration : | P450 Concentration: 2.4 nmol/ml Protein Concentration: 11.3 mg/ml Specific P450 Content: 212 pmol/mg protein |
| Storage Buffer : | 50 mM Tris-acetate (pH 7.6), 250 mM sucrose, 0.25 mM EDTA |
| Gene Name : | Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 [ Rattus norvegicus (Norway rat) ] |
| Official Symbol : | Cyp2d4 |
| Synonyms : | Cyp2d4; cytochrome P450, family 2, subfamily d, polypeptide 4; Cyp2d6; Cyp2d18; Cyp2d22; Cyp2d4v1; Cyp2d4v2; cytochrome P450 2D4; CYPIID18; CYPIID4; Cytochrome P450, subfamily IID4; P450 2D-29/2D-35; P450-CMF3; P450-DB4; cytochrome P450 2D-29; cytochrome P450 2D-35; cytochrome P450 2d18; cytochrome P450, family 2, subfamily d, polypeptide 22; cytochrome P450, subfamily 2D, polypeptide 6; cytochrome P450, subfamily IID, polypeptide 6; cytochrome P450-CMF3; cytochrome P450-DB4; debrisoquine 4-hydroxylase |
| Gene ID : | 171522 |
| mRNA Refseq : | NM_138515 |
| Protein Refseq : | NP_612524 |
| UniProt ID : | Q64680 |
Products Types
| ◆ Recombinant Protein | ||
| Cyp2d4-138R | Active Recombinant Rat Cyp2d4 Protein | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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