Recombinant Rat Pdgfb protein, His/S-tagged

• Cat.No.: Pdgfb-173R
• Product Overview: Recombinant Rat Pdgfb fused with His/S tag was expressed in E. coli.

Specification

• Description: Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. [SUBUNIT] Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. Belongs to the PDGF/VEGF growth factor family.
• Source: E. coli
• Species: Rat
• Tag: His/S
• Form: Lyophilized from sterile PBS, pH 7.4
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Store at -70 centigrade. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: Pdgfb platelet-derived growth factor beta polypeptide [ Rattus norvegicus ]
• Official Symbol: Pdgfb
• Synonyms: PDGFB; platelet-derived growth factor beta polypeptide; platelet-derived growth factor subunit B; PDGF-2; pdgf protein; PDGF subunit B; platelet-derived growth factor B chain; platelet derived growth factor, B polypeptide; Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis); platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); SIS; c-sis
• Gene ID: 24628
• mRNA Refseq: NM_031524
• Protein Refseq: NP_113712
• UniProt ID: Q05028
• Chromosome Location: 7q34
• Pathway: Downstream signal transduction, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Glioma, organism-specific biosystem; Glioma, conserved biosystem
• Function: cell surface binding; cell surface binding; collagen binding; collagen binding; eukaryotic cell surface binding; eukaryotic cell surface binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; platelet-derived growth factor receptor binding; contributes_to platelet-derived growth factor receptor binding; protein heterodimerization activity; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; superoxide-generating NADPH oxidase activator activity; superoxide-generating NADPH oxidase activator activity