Active Recombinant Rat RAB3A Protein, GST/His-tagged

• Cat.No.: RAB3A-709R
• Product Overview: Recombinant Rat RAB3A protein (NP_037150) was expressed in E. coli with GST-His tag.

Specification

• Description: Rab3A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab3A is involved in the process of Ca2+-dependent neurotransmitter release. GTP-Rab3A binds effector molecules, Rabphilin-3 and Rim, localized at synaptic vesicles and the active zone, respectively. These complexes facilitate translocation and docking of the synaptic vesicles to the active zone. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.
• Source: E. coli
• Species: Rat
• Tag: GST/His
• Form: 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol
• Bio-activity: 100 pmol of protein can bind > 80 pmol of GDP.
• Purity: > 90 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: Rab3a RAB3A, member RAS oncogene family [ Rattus norvegicus ]
• Official Symbol: RAB3A
• Synonyms: RAB3A
• Gene ID: 5864
• mRNA Refseq: NM_002866.4
• Protein Refseq: NP_002857.1
• MIM: 179490
• UniProt ID: P20336