| Description : |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined. The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The nucleocapsid phosphoprotein is a structural protein that binds to, protects the viral RNA genome and is involved in packaging the RNA into virus particles. The N protein has been suggested as an antiviral drug target. |
| Source : |
E. coli |
| Species : |
SARS-CoV-2 |
| Tag : |
His |
| Bio-activity : |
Recombinant nucleocapsid protein of SARS-CoV2 is suitable for the studies of antibody generation and other related function assays. |
| Molecular Mass : |
50 kDa |
| AA Sequence : |
MSDNGPQNQRNAPRITFGGPSDSTG SNQNGERSGARSKQRRPQGLPNNTA SWFTALTQHGKEDLKFPRGQGVPIN TNSSPDDQIGYYRRATRRIRGGDGK MKDLSPRWYFYYLGTGPEAGLPYGA NKDGIIWVATEGALNTPKDHIGTRN PANNAAIVLQLPQGTTLPKGFYAEG SRGGSQASSRSSSRSRNSSRNSTPG SSRGTSPARMAGNGGDAALALLLLD RLNQLESKMSGKGQQQQGQTVTKKS AAEASKKPRQKRTATKAYNVTQAFG RRGPEQTQGNFGDQELIRQGTDYKH WPQIAQFAPSASAFFGMSRIGMEVT PSGTWLTYTGAIKLDDKDPNFKDQV ILLNKHIDAYKTFPPTEPKKDKKKK ADETQALPQRQKKQQTVTLLPAADL DDFSKQLQQSMSSADSTQAHHHHHH * |
| Purity : |
≥ 90%, as determined by SDS-PAGE. |
| Storage : |
The protein sample can be stored under sterile conditions at 2-8 centigrade for one month or at -20 to -70 centigrade for three months without detectable loss of activity. |
| Storage Buffer : |
Formulation 20 mM Tris-Cl, pH7.9, 20% glycerol, 100 mM NaCl, 1 mM DTT and 0.5 mM EDTA. |
