Active Recombinant Human HSPA4 Protein (Full Length, 1-641)

• Cat.No.: HSPA4-1560H
• Product Overview: Recombinant Full Length Human HSPA4 Protein (1-641) without tag was expressed in E. coli.

Specification

• Description: Predicted to enable ATP binding activity. Involved in chaperone-mediated protein complex assembly and protein insertion into mitochondrial outer membrane. Located in cytosol and extracellular exosome. Implicated in Chagas disease. Biomarker of chronic obstructive pulmonary disease; rheumatoid arthritis; type 2 diabetes mellitus; and ulcerative colitis.
• Source: E. coli
• Species: Human
• Bio-activity: HSP70 has ATPase activity at the time of manufacture of 3.3 μM phosphate liberated/hr/μg protein in a 200 μL reaction at 37 centigrade (pH7.5) in the presence of 20 μL of 1 mM ATP using a Malachite Green assay.
• Molecular Mass: 70 kDa
• Protein Length: 1-641
• Purity: Near homogeneity by SDS-PAGE
• Applications: ATP Activity Assay, ELISA standard, WB control, Binding Assay
• Storage: Stable for 2 years at -70 centigrade from date of shipment. Please aliquot to avoid repeated freezing and thawing.
• Storage Buffer: Purified HSP70 in 20 mM Tris-HCl, pH 7.5, 50 mM KCl, 1 mM DTT, 5 mM MgCl2.

Gene Information

• Gene Name: HSPA4 heat shock protein family A (Hsp70) member 4 [ Homo sapiens (human) ]
• Official Symbol: HSPA4
• Synonyms: HSPA4; heat shock protein family A (Hsp70) member 4; RY; APG-2; HSPH2; hsp70; hsp70RY; HEL-S-5a; HS24/P52; heat shock 70 kDa protein 4; epididymis secretory sperm binding protein Li 5a; heat shock 70-related protein APG-2; heat shock 70kD protein 4; heat shock protein, 110 kDa; hsp70 RY
• Gene ID: 3308
• mRNA Refseq: NM_002154
• Protein Refseq: NP_002145
• MIM: 601113
• UniProt ID: P34932