Active Recombinant Human HSPA8 protein, His-tagged

• Cat.No.: HSPA8-1558H
• Product Overview: Recombinant full length (aa 1-646) Human HSPA8 Protein was expressed in E. coli with N-terminal His tag.

Specification

• Description: This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 20 mM Tris-HCl, pH 7.5, 50 mM KCl, 1 mM DTT, 5 mM MgCl2
• Bio-activity: HSC70 has ATPase activity at the time of manufacture of 3.2 µM phosphate liberated/hr/µg protein in a 200 µl reaction at 37 centigrade (pH7.5) in the presence of 20 μl of 1 mM ATP using a Malachite Green assay.
• Molecular Mass: 70 kDa
• Storage: Stable for 2 years at -70 centigrade from date of shipment. Please aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: HSPA8 heat shock 70kDa protein 8 [ Homo sapiens ]
• Official Symbol: HSPA8
• Synonyms: HSPA8; heat shock 70kDa protein 8; heat shock 70kD protein 8 , HSPA10; heat shock cognate 71 kDa protein; HSC70; HSC71; HSP73; LPS-associated protein 1; heat shock 70kd protein 10; heat shock cognate protein 54; constitutive heat shock protein 70; lipopolysaccharide-associated protein 1; N-myristoyltransferase inhibitor protein 71; LAP1; HSC54; HSP71; NIP71; HSPA10; MGC29929; MGC131511
• Gene ID: 3312
• mRNA Refseq: NM_006597
• Protein Refseq: NP_006588
• MIM: 600816
• UniProt ID: P11142