Recombinant Human MDM2 protein

• Cat.No.: MDM2-1518H
• Product Overview: Recombinant full length human MDM2 expressed in E.coli.

Specification

• Description: MDM2 (mouse double minute 2) is a major regulator of the tumor suppressor p53 protein. It binds to p53, and is an E3 ubiquitin ligase. Its calculated molecular mass is 52 kDa, but migrates much slower on SDS-PAGE, at a position corresponding to an apparent size of ~95-100 kDa.
• Source: E. coli
• Species: Human
• Form: 50 mM Tris-HCl, (pH7.8), 150 mM NaCl, and 10% glycerol.
• Molecular Mass: 52 kDa
• Storage: Stable for 2 years at -70 centigrade from date of shipment. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: MDM2 Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) [ Homo sapiens ]
• Official Symbol: MDM2
• Synonyms: MDM2; p53 binding protein; E3 ubiquitin-protein ligase Mdm2; HDM2; HDMX; MGC5370
• Gene ID: 4193
• mRNA Refseq: NM_002392
• Protein Refseq: NP_002383
• MIM: 164785
• UniProt ID: Q00987