Recombinant Human NEIL2 protein

• Cat.No.: NEIL2 -1542H
• Product Overview: Recombinant protein was expressed in and purified from E. coli.

Specification

• Description: NEIL2 is a DNA glycosylase involved in base excision repair of oxidative DNA damage. It is a member of the Fpg/Nei/NEIL family of bi-functional DNA glycosylases. Following its glycosylase action, NEIL2 catalyzes sequential β-elimination and δ-elimination reactions via its associated AP lyase. This results in a one-nucleotide gap in DNA containing a 3’ phosphate group. A phosphatase is needed to remove the 3’phosphate group before DNA repair
• Source: E. coli
• Species: Human
• Form: 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 10% glycerol
• Molecular Mass: 38 kDa
• Storage: Store at -70 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: NEIL2 nei endonuclease VIII-like 2 (E. coli) [ Homo sapiens ]
• Official Symbol: NEIL2
• Synonyms: NEIL2; nei endonuclease VIII-like 2 (E. coli); nei like 2 (E. coli); endonuclease 8-like 2; FLJ31644; MGC2832; MGC4505; NEH2; nei like 2; nei homolog 2; nei-like protein 2; endonuclease VIII-like 2; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; NEI2
• Gene ID: 252969
• mRNA Refseq: NM_001135746
• Protein Refseq: NP_001129218
• MIM: 608933
• UniProt ID: Q969S2