Recombinant Human POLH protein

• Cat.No.: POLH-1523H
• Product Overview: Recombinant Human POLH protein was expressed in E. coli.

Specification

• Description: DNA polymerase η is a member of the Y family DNA polymerases. It is involved in translesion synthesis, either error-free or error-prone, depending on the specific types of DNA lesion. Deficiency of Polη in humans leads to the XPV disease.
• Source: E. coli
• Species: Human
• Molecular Mass: 78 kDa
• Usage: Reaction Buffer: 25 mM potassium phosphate (pH 7.0), 5 mM MgCl2, 5 mM DTT, 100 µg/ml BSA, 10% glycerol, 50-100 µM dNTPs.
  Dilution Buffer: 25 mM Tris-HCl (pH 7.5), 2.5 mM β-mercaptoethanol, 50% glycerol.

Gene Information

• Gene Name: POLH polymerase (DNA directed), eta [ Homo sapiens ]
• Official Symbol: POLH
• Synonyms: POLH; polymerase (DNA directed), eta; DNA polymerase eta; RAD30A; XP V; RAD30 homolog A; xeroderma pigmentosum variant type protein; XPV; XP-V; RAD30; FLJ16395; FLJ21978
• Gene ID: 5429
• mRNA Refseq: NM_006502
• Protein Refseq: NP_006493
• MIM: 603968
• UniProt ID: Q9Y253