Recombinant Human POLI protein

• Cat.No.: POLI-1526H
• Product Overview: Recombinant Human POLI protein was expressed in E. coli.

Specification

• Description: DNA polymerase iota is a member of the Y family DNA polymerases. It is involved in translesion synthesis, either error-free or error-prone, depending on the specific types of DNA lesion. Human Polι is unique in that it predominantly incorporates a G opposite the template T during DNA synthesis from undamaged templates.
• Source: E. coli
• Species: Human
• Molecular Mass: 80 kDa
• Usage: Reaction Buffer: 25 mM potassium phosphate (pH 7.0), 5 mM MgCl2, 5 mM DTT, 100 µg/ml BSA, 10% glycerol, 50-100 µM dNTPs.
  Dilution Buffer: 25 mM Tris-HCl (pH 7.5), 2.5 mM β-mercaptoethanol, 50% glycerol.

Gene Information

• Gene Name: POLI polymerase (DNA directed) iota [ Homo sapiens ]
• Official Symbol: POLI
• Synonyms: POLI; polymerase (DNA directed) iota; RAD3OB, RAD30B; DNA polymerase iota; eta2; RAD30 homolog B; polymerase (DNA-directed), iota; RAD30B; RAD3OB
• Gene ID: 11201
• mRNA Refseq: NM_007195
• Protein Refseq: NP_009126
• MIM: 605252
• UniProt ID: Q9UNA4