Growth Differentiation Factor (GDF)
About Growth Differentiation Factor (GDF)
Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-β superfamily proteins. They are produced as inactive preproteinogens, which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked, with the exception of GDF-3 and -9.
GDF plays an important role in a variety of physiological and pathological processes. During development, GDF is involved in cell development, organ formation, embryonic development, and tissue repair. For example, in bone development, GDF participates in bone growth by promoting the secretion of osteoblasts from stem cells. In cartilage growth and repair, GDF regulates the proliferation and activation of chondrocytes and influences the process of cartilage tissue generation and repair. In addition, GDF is involved in the growth and function of cardiovascular, neuromodulatory, anatomical, and other systems.
GDF is also important in hematopoiesis. Research has identified several GDFs involved in hematopoiesis. For example, GDF-11 has been shown to have an effect on regulating HSC quiescence and proliferation. GDF-8 (also known as myoinhibin) is involved in the control of erythropoiesis and affects red blood cell development. GDF-15 is another GDF that plays a role in hematopoiesis and has been associated with a variety of diseases. Understanding the function and regulation of GDF in hematopoiesis is important for both basic research and clinical applications. By studying these growth factors, researchers aim to unravel the complex mechanisms of blood cell formation and differentiation and help develop new therapeutic strategies for a variety of blood disorders, such as anemia, leukemia, and bone marrow failure syndromes.
Available Resources of Growth Differentiation Factor (GDF)
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Growth Differentiation Factor (GDF) Products
Creative BioMart offers a wide range of growth differentiation factor (GDF) related products, such as GDF10, GDF2, GDF1, GDF15, GDF3, GDF5, GDF6, GDF-9, Mstn, which includes recombinant proteins, native proteins, cell & tissue lysates, transfected stable cell lines, protein pre-coupled magnetic beads and other types of products for researchers. This includes recombinant proteins, native proteins, cell & tissue lysates, transfected stable cell lines, protein pre-coupled magnetic beads, and more. You can choose the product that suits your needs based on species, source, tag, etc.
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Technical Support and Educational Resources
Creative BioMart also provides researchers with a series of resources about each growth differentiation factor (GDF), such as involved pathway, protein function, interacting protein, related articles, related gene family, and related research area, please check the product details page.
Our Advantages
Growth hormone (GDF) has a wide range of applications in areas such as tissue regeneration, stem cell research, and biomedical research. Our products, with their high purity and potent biological activity, will provide reliable experimental materials and support for your research. Please contact us now to learn more about Growth Hormone (GDF) and get the products you need. Thank you for your interest!
