aasdhppt
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  • Official Full Name
  • aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  • Background
  • The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
  • Synonyms
  • AASDHPPT; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD PPT; CGI 80; LYS5; 4 phosphopantetheinyl transferase; 4-phosphopantetheinyl transferase; AASD-PPT; ADPPT_HUMAN; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; HAH P; LYS2; LYS5 ortholog; CGI-80
Cat.#:AASDHPPT-480HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AASDHPPT Protein, His-tagged
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Cat.#:AASDHPPT-025HTag:GST
Source (Host):Wheat Germ (in vitro)Species:Human
Product nameRecombinant Human AASDHPPT Protein, GST-tagged
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Cat.#:AASDHPPT-9200HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AASDHPPT, GST-tagged
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Cat.#:AASDHPPT-1067MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse AASDHPPT Protein
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Cat.#:AASDHPPT-389RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat AASDHPPT Protein
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Cat.#:AASDHPPT-175RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey AASDHPPT Protein, His-tagged
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Cat.#:AASDHPPT-5354CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AASDHPPT
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Cat.#:AASDHPPT-3410ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AASDHPPT
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Cat.#:AASDHPPT-797HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AASDHPPT, His-tagged
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Cat.#:AASDHPPT-2HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human AASDHPPT cell lysate
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Involved Pathway

AASDHPPT involved in several pathways and played different roles in them. We selected most pathways AASDHPPT participated on our site, such as Pantothenate and CoA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AASDHPPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pantothenate and CoA biosynthesis
BCAT1; VNN1; PPCS; BCAT2; DPYD; UPB1; VNN2; ENPP3; AASDHPPT; PANK1

Protein Function

AASDHPPT has several biochemical functions, for example, holo-[acyl-carrier-protein] synthase activity, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AASDHPPT itself. We selected most functions AASDHPPT had, and list some proteins which have the same functions with AASDHPPT. You can find most of the proteins on our site.
Function
Related Protein
Function holo-[acyl-carrier-protein] synthase activity
Related Protein AASDHPPT
Function magnesium ion binding
Related Protein NT5C3L; NIM1; ENO4; PPA1; FARSB; MARK1; IDH3B; ATP9B; THG1L; PPA2
Function protein binding
Related Protein FAM125A; TCP1; CENPO; NDUFB11; DMD; CCDC47; STIP1; POLR3C; FGF1; PDGFB

Interacting Protein

AASDHPPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AASDHPPT here. Most of them are supplied by our site. Hope this information will be useful for your research of AASDHPPT.
USP22; TRAF2; SIAH1; EIF1B; HLA-B; BABAM1; MDFI; SLX4; ULK2

AASDHPPT Related Articles

Praphanphoj, V; Sacksteder, KA; et al. Identification of the alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase gene, the human ortholog of the yeast LYSS gene. MOLECULAR GENETICS AND METABOLISM 72:336-342(2001).