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AASDHPPT

  • Official Full Name

    aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

  • Overview

    The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
  • Synonyms

    AASDHPPT; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD PPT; CGI 80; LYS5; 4 phosphopantetheinyl transferase; 4-phosphopantetheinyl transferase; AASD-PPT; ADPPT_HUMAN; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; HAH P; LYS2; LYS5 ortholog; CGI-80;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AASDHPPT-9200H Recombinant Human AASDHPPT, GST-tagged E.coli GST 1-309a.a.
Human AASDHPPT-025H Recombinant Human AASDHPPT Protein, GST-tagged Wheat Germ GST
Human AASDHPPT-797H Recombinant Human AASDHPPT, His-tagged E.coli His
Human AASDHPPT-2HCL Recombinant Human AASDHPPT cell lysate N/A
Human AASDHPPT-1479H Recombinant Human AASDHPPT Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human AASDHPPT-4803H Recombinant Human AASDHPPT protein, His-SUMO-tagged E.coli His-SUMO 1-309aa
Human AASDHPPT-480H Recombinant Human AASDHPPT Protein, His-tagged E.coli His Met1~Ser309
Human AASDHPPT-760HF Recombinant Full Length Human AASDHPPT Protein, GST-tagged In Vitro Cell Free System GST 309 amino acids
Mouse AASDHPPT-1067M Recombinant Mouse AASDHPPT Protein Mammalian Cell His
Mouse Aasdhppt-1458M Recombinant Mouse Aasdhppt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse AASDHPPT-177M-B Recombinant Mouse AASDHPPT Protein Pre-coupled Magnetic Beads HEK293
Mouse AASDHPPT-177M Recombinant Mouse AASDHPPT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AASDHPPT-389R Recombinant Rat AASDHPPT Protein Mammalian Cell His
Rat AASDHPPT-44R Recombinant Rat AASDHPPT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AASDHPPT-44R-B Recombinant Rat AASDHPPT Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque AASDHPPT-175R Recombinant Rhesus monkey AASDHPPT Protein, His-tagged Mammalian Cell His
Rhesus Macaque AASDHPPT-4R Recombinant Rhesus Macaque AASDHPPT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque AASDHPPT-4R-B Recombinant Rhesus Macaque AASDHPPT Protein Pre-coupled Magnetic Beads HEK293
Zebrafish AASDHPPT-3410Z Recombinant Zebrafish AASDHPPT Mammalian Cell His
Chicken AASDHPPT-5354C Recombinant Chicken AASDHPPT Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AASDHPPT Related Articles

AASDHPPT involved in several pathways and played different roles in them. We selected most pathways AASDHPPT participated on our site, such as Pantothenate and CoA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AASDHPPT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pantothenate and CoA biosynthesisDPYS;BCAT1;UPB1;DPYD;VNN1;VNN2;ENPP3;AASDHPPT;PANK2

AASDHPPT has several biochemical functions, for example, holo-[acyl-carrier-protein] synthase activity, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AASDHPPT itself. We selected most functions AASDHPPT had, and list some proteins which have the same functions with AASDHPPT. You can find most of the proteins on our site.

Function Related Protein
holo-[acyl-carrier-protein] synthase activity
magnesium ion bindingWRN;NUDT16;PSPH;IMPA1;TSSK4;WEE2;PRPS1L1;ENO4;MTPAP
protein bindingRIPK4;SALL2;HESX1;OTUD7B;PCID2;HCLS1;CCDC110;ARL4A;C14orf166

AASDHPPT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AASDHPPT here. Most of them are supplied by our site. Hope this information will be useful for your research of AASDHPPT.

USP22; TRAF2; SIAH1; EIF1B; HLA-B; BABAM1; MDFI; SLX4; ULK2

Praphanphoj, V; Sacksteder, KA; et al. Identification of the alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase gene, the human ortholog of the yeast LYSS gene. MOLECULAR GENETICS AND METABOLISM 72:336-342(2001).
  • Q&As
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