ABCB8
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Official Full Name
ATP-binding cassette, sub-family B (MDR/TAP), member 8
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Overview
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MDR/TAP subfamily.Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation.The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol.This protein may also play a role in the transport of phospholipids into mitochondrial membranes. -
Synonyms
ABCB8; ATP-binding cassette, sub-family B (MDR/TAP), member 8; ATP-binding cassette sub-family B member 8, mitochondrial; EST328128; M ABC1; MABC1; mitochondrial ABC protein; mitochondrial ATP-binding cassette 1; M-ABC1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In vitro E. coli expression system
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- SUMO
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ABCB8-8128H | Recombinant Human ABCB8 protein, His & T7-tagged | E.coli | His/T7 | Val472~Ser735 (Accession # Q9NUT2) | |
Human | ABCB8-9151HCL | Recombinant Human ABCB8 293 Cell Lysate | HEK293 | N/A | ||
Human | ABCB8-2464H | Recombinant Human ABCB8 Transmembrane protein, His-SUMO-tagged | In vitro E. coli expression system | His-SUMO | 38-693aa | |
Human | ABCB8-0158H | Recombinant Human ABCB8 Protein (Val472-Ser735), N-His-tagged | E.coli | N-His | Val472-Ser735 | |
Mouse | Abcb8-8129M | Recombinant Mouse Abcb8 protein, His & T7-tagged | E.coli | His/T7 | Gly468~Ala717 (Accession # Q9CXJ4) | |
Mouse | ABCB8-1095M | Recombinant Mouse ABCB8 Protein | Mammalian Cell | His | ||
Mouse | ABCB8-193M-B | Recombinant Mouse ABCB8 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | ABCB8-193M | Recombinant Mouse ABCB8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | Abcb8-8130R | Recombinant Rat Abcb8 protein, His & T7-tagged | E.coli | His/T7 | Gly468~Gln714 (Accession # Q5RKI8) | |
Rat | ABCB8-400R | Recombinant Rat ABCB8 Protein | Mammalian Cell | His | ||
Rat | ABCB8-55R-B | Recombinant Rat ABCB8 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | ABCB8-55R | Recombinant Rat ABCB8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mus musculus (Mouse) | RFL35820MF | Recombinant Full Length Mouse Atp-Binding Cassette Sub-Family B Member 8, Mitochondrial(Abcb8) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (39-717) | |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL34668PF | Recombinant Full Length Pongo Abelii Atp-Binding Cassette Sub-Family B Member 8, Mitochondrial(Abcb8) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (39-718) | |
Rattus norvegicus (Rat) | RFL13678RF | Recombinant Full Length Rat Atp-Binding Cassette Sub-Family B Member 8, Mitochondrial(Abcb8) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (39-714) | |
Zebrafish | ABCB8-2327Z | Recombinant Zebrafish ABCB8 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ABCB8 Related Articles
ABCB8 involved in several pathways and played different roles in them. We selected most pathways ABCB8 participated on our site, such as ABC transporters, ABC-family proteins mediated transport, Mitochondrial ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCB8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ABC transporters | ABCC3;ABCB6;ABCC10;ABCG5;ABCB10;ABCA9;ABCG3;Abca2;ABCG1 |
ABC-family proteins mediated transport | EIF2S3;EIF2S1;ABCA8;ABCB8;ABCG4B;CFTR;ABCC9;ABCD3B;EIF2S1A |
Mitochondrial ABC transporters | |
Transmembrane transport of small molecules | SLC35D1A;ADD3A;SLC2A7;MFSD7B;RHCGL1;SLC6A20B;SLC6A18;ATP2B3A;SLC22A7B.1 |
ABCB8 has several biochemical functions, for example, ATP binding, ATPase activity, coupled to transmembrane movement of substances, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCB8 itself. We selected most functions ABCB8 had, and list some proteins which have the same functions with ABCB8. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | BLK;RECQL;HSPA5;PSMC3;TAOK1;TTLL1;NLK;SLFN5;NME3 |
ATPase activity, coupled to transmembrane movement of substances | ABCB4;ABCA3;ABCD3B;ABCA8;ABCC8;DPY19L2;ABCG2;ABCG3;ABCB6A |
transporter activity | SLC4A2B;AP3D1;CLVS1;ATP6V0E1;SLC5A11;AQP3A;ATP5G3;ABCC1;SLC22A17 |
ABCB8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCB8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCB8.
SAT1; NOA1
- Q&As
- Reviews
Q&As (12)
Ask a questionWe provide tag customization services, and you can communicate with us about specific customization needs at any time.
Yes, we can customize proteins with different purities according to your needs.
In general, adding small tags has very little effect on protein activity, but we cannot confirm the specific effect of adding tags on protein activity.
The specific price will vary depending on the customization needs. You can communicate with us about the specific customization needs first, and then we will provide you with price information
Yes, you put forward this demand when purchasing, and we will deliver according to your demand.
Yes, we can customize protein products with different endotoxin levels.
Yes, this product is eligible for this promotion.
Our commonly used purification methods include hydrophobic chromatography, affinity chromatography, ion exchange chromatography, salting out, molecular sieve, etc.
You can make this request when purchasing, and we will send you the relevant protocol.
Trehalose can prevent protein secondary structure changes, elongation and aggregation during freeze-drying.
After the customer purchases the product, we will ship it as soon as possible, but the arrival time is related to your specific location. If it is a custom-made product, the delivery time will be longer.
Incubate with the primary antibody overnight at 4°C.
Customer Reviews (2)
Write a reviewThe technicians are very professional and provided me with some useful suggestions related to experiments.
The customized communication was very smooth, and I also received my customized protein products very quickly.
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