ABCF3
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Official Full Name
ATP-binding cassette, sub-family F (GCN20), member 3
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Synonyms
ABCF3; ATP-binding cassette, sub-family F (GCN20), member 3; ATP-binding cassette sub-family F member 3; EST201864; FLJ11198;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ABCF3 Related Articles
ABCF3 involved in several pathways and played different roles in them. We selected most pathways ABCF3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ABCF3 has several biochemical functions, for example, ATP binding, ATPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCF3 itself. We selected most functions ABCF3 had, and list some proteins which have the same functions with ABCF3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | EPHB4B;MAT1A;NIM1K;DDX3Y;BCR;LCK;ACTR3;DGUOK;SMC1A |
| ATPase activity | SMARCA4A;DDX3X;CHD1L;PMS2;MLH3;DNA2;Abca2;ABCD1;CARNS1 |
| protein binding | EYA3;NAT2;RXRA;SPHK1;RUNX3;MEOX2;CXXC5;CEBPA;DCX |
ABCF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCF3.
TRIM27; 80125; FCHSD2; DNALI1; DLEU1; MOCS2; SPP1; TBPL1; LAMTOR1; NOA1; TOE1; SLC35E1; HIRIP3
- Q&As
- Reviews
Q&As (20)
Ask a questionThe cellular function of ABCF3, also known as ABC50 (ATP-binding cassette subfamily F member 3), is primarily related to its role as an ATP-binding cassette (ABC) transporter. It is involved in the transport of molecules across cellular membranes, facilitating the efflux of substrates from cells.
ABCF3 is believed to be expressed in various tissues and cell types, suggesting a broad expression profile.
Transcriptional regulation, post-translational modifications, or interactions with other proteins may influence ABCF3 function.
ABCF3 has been implicated in drug resistance or multidrug resistance in cancer cells. It is believed to contribute to the efflux of chemotherapeutic drugs from cancer cells, reducing their effectiveness and contributing to drug resistance.
While specific disease associations with ABCF3 are not widely reported, dysregulation of ABC transporters, including those in the F subfamily, has been implicated in drug resistance in cancer cells and certain genetic disorders
As an ATP-binding cassette (ABC) transporter, ABCF3 likely possesses the characteristic ABC domains responsible for ATP binding and hydrolysis, as well as transmembrane domains that form the transport channel.
ATP-binding cassette subfamily F member 3 (ABCF3) belongs to a member of the ATP-binding cassette (ABC) transporter superfamily.
It displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B.
ABCF3 may be involved in cellular signaling pathways or contribute to cellular homeostasis through its transport activity.
TRI27 and FCSD2 has binary interactions with ABCF3
Conditions involving altered cellular transport processes, drug response, or cellular homeostasis could potentially be associated with ABCF3 dysregulation.
ABCF3 is primarily localized to the plasma membrane, but it may also be found in intracellular organelles involved in transport, such as the endoplasmic reticulum.
It lacks transmembrane domains and is probably not involved in transport.
ABCF3 is primarily localized to the plasma membrane, but it may also be found in intracellular organelles involved in transport processes, such as the endoplasmic reticulum.
Factors such as transcriptional regulation, post-translational modifications, or protein-protein interact
Given its involvement in cellular transport processes, it is possible that ABCF3 may have implications in cellular metabolism, cellular signaling, or other cellular functions.
Variations or dysregulation of ABCF3 expression could potentially influence drug response or alter cellular transport processes
ABCF3 are mainly present in species of human, mouse, rat, slime mold and A.thaliana.
While ABC transporters can transport a wide range of substrates, including lipids, nucleotides, peptides, and drugs, further research is needed to identify the precise substrates and their functional relevance for ABCF3.
ABCF3 consists of two transmembrane domains (TMDs) that form the transport channel across the cell membrane and two nucleotide-binding domains (NBDs) responsible for ATP binding and hydrolysis.
Customer Reviews (5)
Write a reviewI appreciated that the protein did not cause any irritation or adverse effects on my skin during handling.
The ABCF3 product exhibited excellent activity.
The protein product's reliability and consistent results justified the investment for my long-term experiments.
They promptly addressed my inquiries and providing helpful guidance throughout the ordering process.
I received excellent technical support from the company
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