Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

ACAP2

  • Official Full Name

    ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

  • Overview

    Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the ACAP2 gene.
  • Synonyms

    ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2; centaurin, beta 2 , CENTB2; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; CNT B2; KIAA0041; ACAP 2; Arf GAP with coiled coil ANK repeat and PH domains 2; CENT B 2; Centaurin beta2; CENTB 2; CENTB2; Cntb2; Similar to yeast ZINC FINGER PROTEIN GCS1; centaurin-beta-2; centaurin, beta 2; OTTHUMP00000208844; Arf GAP with coiled coil, ANK repeat and PH domains 2; CNT-B2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACAP2-0003H Recombinant Human ACAP2 Protein, GST-Tagged Wheat Germ GST
Human ACAP2-9274H Recombinant Human ACAP2, His-tagged E.coli His 479-778a.a.
Human ACAP2-9109HCL Recombinant Human ACAP2 293 Cell Lysate HEK293 N/A
Human ACAP2-1264H Recombinant Human ACAP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ACAP2-2574HF Recombinant Full Length Human ACAP2 Protein, GST-tagged In Vitro Cell Free System GST 778 amino acids
Mouse ACAP2-1169M Recombinant Mouse ACAP2 Protein Mammalian Cell His
Mouse Acap2-1488M Recombinant Mouse Acap2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ACAP2-243M-B Recombinant Mouse ACAP2 Protein Pre-coupled Magnetic Beads HEK293
Mouse ACAP2-243M Recombinant Mouse ACAP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ACAP2-442R Recombinant Rat ACAP2 Protein Mammalian Cell His
Rat ACAP2-97R Recombinant Rat ACAP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ACAP2-97R-B Recombinant Rat ACAP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ACAP2-200R Recombinant Rhesus monkey ACAP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ACAP2-29R Recombinant Rhesus Macaque ACAP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ACAP2-29R-B Recombinant Rhesus Macaque ACAP2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ACAP2-5941Z Recombinant Zebrafish ACAP2 Mammalian Cell His
Chicken ACAP2-1686C Recombinant Chicken ACAP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ACAP2 Related Articles

ACAP2 involved in several pathways and played different roles in them. We selected most pathways ACAP2 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisKIT;ARAP2;STAM;CYTH1;CHMP6;MVB12BB;CAPZB;VPS37A;KIF5B

ACAP2 has several biochemical functions, for example, GTPase activator activity, Rab GTPase binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACAP2 itself. We selected most functions ACAP2 had, and list some proteins which have the same functions with ACAP2. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityAGFG1A;RGS5B;ARFGAP2;TBC1D14;TBC1D25;ECT2;RP2;TSC2;DLC1
Rab GTPase bindingZFYVE20;ANXA2;RAB3GAP1;RPH3AL;ERC1;RIMS1;USP6NL;HACE1;STXBP5L
metal ion bindingDOM3Z;ZNF559-ZNF177;ZBTB18;MMP13A;ZNF280C;UQCRC2A;AGAP1;CELA1;CTDSPL

ACAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACAP2.

HSPB1; pi3p; k1_vaccw; PDK3; Tgs1; Naa10

Miyamotoa, Y; Yamamori, N; et al. Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. MOLECULAR BIOLOGY OF THE CELL 25:1532-1542(2014).
Hong, JY; Liu, X; et al. Genetic Aberrations in Imatinib-Resistant Dermatofibrosarcoma Protuberans Revealed by Whole Genome Sequencing. PLOS ONE 8:-(2013).
  • Q&As
  • Reviews

Q&As (10)

Ask a question
Is there any discount for ACAP2 recombinant protein? 12/25/2022

We are offering a 10% discount on all products for a limited time. The clock is ticking down. Be sure to take advantage of our holiday promotions!

What applications can recombinant ACAP2 protein be used for? 09/16/2022

Recombinant ACAP2 protein can be used for various applications, such as biochemical assays, protein-protein interaction studies, and drug discovery. It can also be used as an immunogen for antibody production or as a standard in ELISA assays.

Can the recombinant ACAP2 protein be used in in vitro or in vivo assays? 09/16/2022

Recombinant ACAP2 protein can be used in both in vitro and in vivo assays, depending on your research needs. In vitro assays can include biochemical assays, protein-protein interaction studies, and enzymatic assays, while in vivo assays can include cell-based assays or animal models.

What is the role of ACAP2 in cytokinesis? 09/05/2022

ACAP2 is involved in the regulation of cytokinesis by controlling the activity of RhoA, a small GTPase that plays a critical role in the formation of the contractile ring. ACAP2 interacts with RhoA and regulates its activity, which is necessary for the proper formation and contraction of the contractile ring.

What is the function of ACAP2 in endocytic trafficking? 08/12/2022

ACAP2 is involved in the regulation of clathrin-mediated endocytosis (CME) by controlling the formation of clathrin-coated vesicles. It interacts with multiple proteins such as AP2, Eps15, and dynamin, and regulates the activity of Arf6 GTPase, which is essential for the formation of clathrin-coated vesicles.

Can the recombinant human ACAP2 protein be customized or modified to suit specific research needs? 06/18/2021

Creative BioMart offers customization or modification services for recombinant ACAP2 protein, such as adding tags or modifying the protein sequence.

What is the price of recombinant human ACAP2 protein? 10/12/2020

It depends on the specific product. Generally, the price is based on factors such as purity, quantity, and functional activity. Please submit an inquiry form for specific products, or contact our technical support staff for consultation.

Does the recombinant ACAP2 protein have any post-translational modifications? 10/07/2020

The presence or absence of post-translational modifications in recombinant ACAP2 protein can vary depending on the expression system and the purification method used. We support custom production of recombinant proteins, and you can describe your specific research requirements when submitting the online inquiry form.

How does ACAP2 regulate cell migration? 10/07/2020

ACAP2 is involved in the regulation of cell migration by controlling the activity of Rac1, a small GTPase that plays a critical role in the formation of lamellipodia and membrane ruffling. ACAP2 interacts with Rac1 and regulates its activity, which is necessary for the formation of these structures during cell migration.

What is the significance of ACAP2 in cancer? 09/18/2020

ACAP2 has been shown to play a critical role in the regulation of cell proliferation and survival, and its dysregulation has been linked to the development and progression of various types of cancer. ACAP2 has been shown to be upregulated in several types of cancer, including breast, lung, and liver cancer, and its inhibition has been proposed as a potential therapeutic strategy for cancer treatment.

Customer Reviews (3)

Write a review
Reviews
08/10/2021

    I am very satisfied with the recombinant human ACAP2 protein. The product was of high quality and helped me achieve excellent results.

    10/12/2020

      I have had nothing but positive experiences with Creative BioMart. Their recombinant ACAP2 proteins are consistently high-quality and their customer service is excellent.

      09/18/2020

        Thanks to Creative BioMart's recombinant ACAP2 proteins, my research has progressed much more quickly than I had anticipated.

        Ask a Question for All ACAP2 Products

        Required fields are marked with *

        My Review for All ACAP2 Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends