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ACSF2

  • Official Full Name

    acyl-CoA synthetase family member 2

  • Synonyms

    ACSF2; acyl-CoA synthetase family member 2; acyl-CoA synthetase family member 2, mitochondrial; ACSMW; FLJ20920; mitochondrial; ACSF 2; ACSF2_HUMAN; Acyl CoA synthetase family member 2; Acyl CoA synthetase family member 2 mitochondrial; AVYV493; PPARG binding long chain fatty acid acyl Co A ligase like; Putative uncharacterized protein FLJ20920; PPARG binding, long chain fatty acid acyl Co-A ligase like;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACSF2-9317H Recombinant Human ACSF2, His-tagged E.coli His 336-615a.a.
Human ACSF2-47H Recombinant Human ACSF2 protein, His-tagged E.coli His
Human ACSF2-193H Recombinant Human ACSF2 Protein, GST-tagged Wheat Germ GST
Human ACSF2-9078HCL Recombinant Human ACSF2 293 Cell Lysate HEK293 N/A
Human ACSF2-194H Recombinant Human ACSF2 protein, GST-tagged E. coli GST 336-615 aa
Human ACSF2-4734H Recombinant Human ACSF2 protein, His-tagged E.coli His 42-615aa
Human ACSF2-787HF Recombinant Full Length Human ACSF2 Protein, GST-tagged In Vitro Cell Free System GST 615 amino acids
Human ACSF2-49H Recombinant Human ACSF2 Protein, His-tagged E.coli N-His Cys322-Leu615
Mouse ACSF2-1223M Recombinant Mouse ACSF2 Protein Mammalian Cell His
Mouse ACSF2-270M-B Recombinant Mouse ACSF2 Protein Pre-coupled Magnetic Beads HEK293
Mouse ACSF2-270M Recombinant Mouse ACSF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ACSF2-468R Recombinant Rat ACSF2 Protein Mammalian Cell His
Rat ACSF2-124R-B Recombinant Rat ACSF2 Protein Pre-coupled Magnetic Beads HEK293
Rat Acsf2-50R Recombinant Rat Acsf2 Protein, His-tagged E.coli N-His Thr375-Leu615
Rat ACSF2-124R Recombinant Rat ACSF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey ACSF2-268C Recombinant Cynomolgus ACSF2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey ACSF2-18C Recombinant Cynomolgus Monkey ACSF2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey ACSF2-18C-B Recombinant Cynomolgus Monkey ACSF2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish ACSF2-4374Z Recombinant Zebrafish ACSF2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ACSF2 Related Articles

ACSF2 involved in several pathways and played different roles in them. We selected most pathways ACSF2 participated on our site, such as Fatty Acyl-CoA Biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fatty Acyl-CoA BiosynthesisACOT8;ACOT9.1;ACOT13;ACSF3;SLC25A1;ACOT11B;THEM5;ACOT10;ACOT12
Fatty acid, triacylglycerol, and ketone body metabolismACOT11B;PLIN2;AGPAT2;ELOVL1A;MED10;ACOT9.1;GRHL1;DGAT1B;AGPAT6
MetabolismAPOF;SLC25A1A;ARSH;HAS1;SLC5A9;SLC35D2;UCP2;TPMT.2;GLTPD1
Metabolism of lipids and lipoproteinsFA2H;GC;ACOT12;FABP11B;DPEP1;OSBP;MED8;ABHD3;CYP2AD6
Triglyceride BiosynthesisACOT12;SLC25A1A;SLC25A1;ACOT11B;ACSF3;ACOT6;ACOT9.1;ACOT13;DGAT1B

ACSF2 has several biochemical functions, for example, ATP binding, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSF2 itself. We selected most functions ACSF2 had, and list some proteins which have the same functions with ACSF2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingLCK;CKMT2;CSNK1G2B;CSNK1G2;ACSM4;ATAD1B;SNRK;PFKM;TLK1B
ligase activityRBBP6;UBE2G1B;LIPT2;TRIM13;NSMCE2;UBE2IB;ZFP91;RNF25;TRIM6
protein bindingCCNB3;DUSP14;RAP1B;TAF1D;FBXO4;FUBP3;PHAX;ALS2;FAM118A

ACSF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSF2.

ARL6IP1; CMTM5; AGTRAP; CREB3; tnp_34; pi3p; SIRT4

Celis, JE; Cabezon, T; et al. Molecular characterization of apocrine carcinoma of the breast: Validation of an apocrine protein signature in a well-defined cohort. MOLECULAR ONCOLOGY 3:220-237(2009).
  • Q&As
  • Reviews

Q&As (10)

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Are there any therapeutic implications of targeting ACSF2? 11/16/2022

ACSF2 inhibitors have been proposed as a potential therapeutic strategy for the treatment of metabolic disorders, although further research is needed to validate this approach.

What is the substrate specificity of ACSF2? 07/11/2022

ACSF2 has a broad substrate specificity and can activate a range of long-chain fatty acids including palmitic acid, oleic acid, and arachidonic acid.

What is the mechanism of ACSF2-mediated fatty acid activation? 03/19/2022

ACSF2 activates fatty acids by converting them into their acyl-CoA derivatives through the use of ATP and CoA.

What is the role of ACSF2 in cellular stress response? 09/27/2021

ACSF2 has been shown to play a role in the cellular stress response by regulating the activation of AMPK and the expression of stress response genes.

What is the role of ACSF2 in cancer? 10/09/2020

ACSF2 has been shown to play a role in tumor growth and progression in several types of cancer, including colorectal cancer and hepatocellular carcinoma.

Where is ACSF2 primarily expressed? 09/17/2020

ACSF2 is highly expressed in the liver and also in other tissues such as the brain, heart, and muscle.

How does ACSF2 affect lipid droplet dynamics? 04/28/2020

ACSF2 has been shown to play a role in the regulation of lipid droplet dynamics by regulating the activity of lipases and promoting the formation of lipid droplets.

What is the effect of ACSF2 overexpression on fatty acid metabolism? 11/10/2019

Overexpression of ACSF2 has been shown to increase fatty acid oxidation and decrease fatty acid synthesis in hepatocytes.

How does ACSF2 affect insulin sensitivity? 06/11/2019

ACSF2 has been shown to play a role in insulin sensitivity by regulating glucose uptake and lipid metabolism in skeletal muscle cells.

How is ACSF2 involved in the regulation of inflammation? 11/19/2018

ACSF2 has been shown to regulate the production of inflammatory cytokines in macrophages and may play a role in the development of inflammatory diseases.

Customer Reviews (5)

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Reviews
10/07/2021

    Super fast shipping and excellent customer service. Will definitely buy from again.

    09/14/2021

      Great product! Really satisfied with the quality of the recombinant protein.

      07/13/2020

        Wonderful product!

        09/25/2018

          Overall, I highly recommend this recombinant protein and the manufacturer for their excellent product and service.

          08/21/2018

            I was impressed with the strict quality control measures the manufacturer had in place to ensure consistent quality.

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